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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

340
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
340

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Related Experiment Video

Updated: Aug 18, 2025

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

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Watch and wait for Rectal Cancer: A 9 year Experience.

C Cosgrove1, Raj Spence1, L Convie1

  • 1General Surgical Unit, Ulster Hospital, Upper Newtownards Road, BT16 1RH.

The Ulster Medical Journal
|December 7, 2022
PubMed
Summary
This summary is machine-generated.

For locally advanced rectal cancer, neoadjuvant chemoradiotherapy enables a watch and wait program for many patients. A significant majority of these patients avoided major surgery, demonstrating the program's effectiveness in rectal cancer treatment.

Keywords:
Rectal cancerlong course chemoradiotherapywatch and wait

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Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Oncology

Background:

  • Neoadjuvant long course chemoradiotherapy is standard for locally advanced rectal cancer.
  • It aids in tumor reduction, downstaging, and improving resection margins.
  • This approach aims to reduce local recurrence rates.

Purpose of the Study:

  • To evaluate outcomes of patients with rectal cancer undergoing neoadjuvant chemoradiotherapy.
  • To assess the efficacy and safety of a watch and wait program post-neoadjuvant therapy.
  • To determine the long-term disease-free survival and need for surgery in this cohort.

Main Methods:

  • Analysis of a prospective database from 2011-2019.
  • Inclusion of all patients with rectal cancer treated with neoadjuvant chemoradiotherapy.
  • Focus on patients who entered a watch and wait program due to complete response.

Main Results:

  • 180 of 532 rectal cancer patients received neoadjuvant chemoradiotherapy.
  • 61 patients (11%) entered the watch and wait program after complete response.
  • 40 patients (65%) remained disease-free, 12 (20%) required surgery, and 9 (15%) had palliative care.

Conclusions:

  • Neoadjuvant chemoradiotherapy is a key treatment for locally advanced rectal cancer.
  • 34% of treated patients entered a watch and wait program.
  • The majority of patients in the watch and wait program successfully avoided major rectal surgery.