Perspectives on Using Fast-Dissolving Paracetamol for Mild-to-Moderate Pain Management in Elderly or Diabetic...

Area of Science:

• Pharmacology
• Gastroenterology
• Pain Management

Background:

• Delayed gastric emptying impacts medication efficacy, particularly in elderly and diabetic patients.
• Effective pain management is crucial for these vulnerable populations.
• Fast-dissolving formulations may overcome absorption barriers.

Purpose of the Study:

• To explore healthcare professionals' perspectives on using fast-dissolving paracetamol (FD-APAP) for pain relief.
• To assess the suitability of FD-APAP in patients with delayed gastric emptying, including the elderly and diabetics.
• To identify barriers and facilitators in using FD-APAP for pain management.

Main Methods:

• A two-step modified Delphi consensus study involving 10 general practitioners and 4 endocrinologists.
• In-depth discussions on FD-APAP evidence for delayed gastric emptying populations.
• A survey to reach ≥70% consensus on FD-APAP's relevance and utility.

Main Results:

• Unanimous consensus that FD-APAP is favorable and relevant for pain management in elderly and diabetic patients.
• General practitioners emphasized considering comorbidities in diabetic patients for optimal pain management.
• FD-APAP's rapid disintegration and absorption were recognized as beneficial.

Conclusions:

• FD-APAP is a relevant and useful option for pain management in elderly and diabetic patients with delayed gastric emptying.
• The formulation allows for effective pain treatment with potentially fewer side effects in susceptible individuals.
• Addressing comorbidities is important for comprehensive pain management in diabetic patients.