Related Experiment Video
Updated: Aug 18, 2025

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
Published on: March 7, 2019
COVID-19 Exposure Unmasking Systemic Amyloidosis With Hepatic Predominance
Jose R Russe-Russe1, Chiya Abramowitz2, James R Pellegrini1
1Internal Medicine, Nassau University Medical Center, East Meadow, USA.
COVID-19 infection may accelerate systemic amyloidosis, particularly hepatic involvement, by triggering an effective immune response. This study explores amyloid light chain (AL) and serum amyloid A (AA) protein roles in COVID-19, examining their impact on disease severity.
Area of Science:
- Medicine
- Immunology
- Pathology
Background:
- Amyloidosis involves misfolded proteins (beta-pleated sheets) depositing in organs like the heart, kidneys, and liver.
- Common types include amyloid light chain (AL) and serum amyloid A (AA) proteins, with distinct origins and clinical associations.
- Serum AA protein levels can indicate severity and monitor disease in infections like COVID-19.
More Related Videos
08:25Mass Cytometry Analysis of Systemic and Local Immune Responses in Hepatocellular Carcinoma
Published on: April 25, 2025
10:04Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging
Published on: October 20, 2017
Related Concept Videos
Amyloid Fibrils
Hepatic Portal System
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...