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Updated: Aug 18, 2025

Generation of Transgenic C. elegans by Biolistic Transformation
Published on: August 23, 2010
[Transgenesis in Worms: Candidates for an Ideal Model]
I S Sukhikh1,2, M Yu Biryukov1, A G Blinov1,3
1Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia.
Abstract:
Transgenesis is an important and often irreplaceable method to study numerous processes of animal life. To create animal transgenic lines, it is necessary to have a suitable model organism that has necessary traits for efficient and affordable transgenesis. The concise review characterizes the existing model organisms of different taxa for which an efficient transgenesis protocol has been developed. Special attention is paid to flatworms and, in particular, Macrostomum lignano as a promising model organism for studying aging, regeneration, and carcinogenesis.
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