Related Experiment Video
Updated: Aug 18, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Photoinduced Pd-Catalyzed Csp2-H/Csp3-H Dehydrocoupling Reaction Employing Polyhaloaromatics as the Dehydrogenating
Lin Chen1, Kai Jiang1, Guohui Zeng1
1School of Chemistry and Chemical Engineering, South China University of Technology, 381 Wushan, Tianhe, Guangzhou 510640, China.
Abstract:
A mild strategy for intermolecular cross-dehydrocoupling of Csp2-H bonds and Csp3-H bonds has been developed with the aid of photoinduced Pd catalysis. Polyhalogenated arenes can be used as the efficient dehydrogenating agent, which enables multifold transfer of carbon radical to avoid the production of stoichiometric or excess wasted arenes. In this strategy, substituted styrenes and N-arylacrylamides with simple ethers or amides as the coupling partners gives the corresponding internal alkenes and benzolactams with moderate to good yield.
More Related Videos
11:44Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
09:35Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Related Concept Videos
Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation...
Nucleophilic Aromatic Substitution: Elimination–Addition
Reduction of Benzene to Cyclohexane: Catalytic Hydrogenation
Hydrolysis of Chlorobenzene to Phenol: Dow Process
Thermal and Photochemical Electrocyclic Reactions: Overview
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation