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Optimised conformal total body irradiation: a heterogeneous practice, so where next?
Sarah Misson-Yates1,2, Rissa Cunningham1, Regina Gonzalez1
1Department of Medical Physics, Guy's Cancer Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.
The British Journal of Radiology
|December 8, 2022
Summary
Advanced planning for total body irradiation (TBI) using volumetric arc therapy is emerging. This review examines current protocols for TBI planning and dosimetry verification, highlighting the need for standardization.
Area of Science:
- Radiation Oncology
- Medical Physics
Background:
- Volumetric arc therapy and inverse planning are established radiotherapy techniques.
- Their application in total body irradiation (TBI) is recent, with limited established guidelines.
- This has resulted in varied planning and verification approaches.
Purpose of the Study:
- To review current advanced planning and dosimetry verification protocols for optimized conformal TBI.
- To provide a foundation for assessing the need for increased standardization in TBI.
Main Methods:
- Literature review of advanced planning techniques in TBI.
- Analysis of dosimetry verification strategies for conformal TBI.
- Synthesis of current protocols and identification of variations.
Main Results:
- Heterogeneous approaches in TBI planning and verification are prevalent.
- Current advanced techniques offer potential for optimized conformal TBI.
- Significant variations exist in the implementation of these techniques.
Conclusions:
- There is a clear need for greater standardization in total body irradiation planning and verification.
- Standardized protocols will enhance consistency and quality of care in TBI.
- Further research is required to develop and validate standardized TBI protocols.
