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Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

72
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
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Related Experiment Video

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Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food
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Human Listeriosis.

Merel M Koopmans1, Matthijs C Brouwer1, José A Vázquez-Boland2

  • 1Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, the Netherlands.

Clinical Microbiology Reviews
|December 8, 2022
PubMed
Summary

Listeria monocytogenes, a foodborne pathogen, causes severe invasive infections like meningitis and sepsis. Understanding its epidemiology and pathogenesis is crucial for preventing and treating listeriosis, a life-threatening illness.

Keywords:
Listeria monocytogenesbacterial geneticsepidemiologyhistopathologylisteriosisneurolisteriosispathophysiologypregnancy-related listeriosis

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Food Safety

Background:

  • Listeria monocytogenes is a Gram-positive bacterium responsible for listeriosis, a severe foodborne illness.
  • Listeriosis can lead to invasive infections including bacteremia, meningitis, and pregnancy-associated complications.
  • It is a significant cause of hospitalization in Western countries.

Purpose of the Study:

  • To provide a comprehensive overview of human listeriosis.
  • To detail the characteristics of Listeria monocytogenes.
  • To cover epidemiology, pathogenesis, clinical aspects, and prevention strategies.

Main Methods:

  • Review of existing literature on Listeria monocytogenes and listeriosis.
  • Analysis of data from international surveillance systems.
  • Integration of findings from whole genome studies and pathophysiological investigations.

Main Results:

  • Listeria monocytogenes is a versatile pathogen with diverse evolutionary paths.
  • Invasive listeriosis presents with varied clinical manifestations depending on the affected population.
  • Surveillance and genetic data aid in identifying contamination sources.

Conclusions:

  • Effective prevention and treatment of listeriosis require a thorough understanding of the pathogen and disease.
  • Continued research into Listeria monocytogenes' evolution and pathogenicity is essential.
  • Public health strategies must address food safety and risk group protection.