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Evaluation of Renal Function and Urinalysis in Children With Simple Febrile Convulsions

Amirmahdi Ahmadi1, Fakhreddin Shariatmadari2, Parsa Yousefichaijan2

  • 1Arak University of Medical Sciences, Arak, Iran.

Clinical Pediatrics
|December 8, 2022
PubMed

Insights

Febrile convulsions (FC) in children can affect kidney function, leading to decreased estimated glomerular filtration rate (eGFR). Renal function assessments and urinalysis are recommended for all children experiencing FC to detect potential issues.

Area of Science:

  • Pediatrics
  • Nephrology
  • Clinical Medicine

Background:

  • Febrile convulsion (FC) is a common pediatric seizure disorder.
  • Febrile illnesses are known to impact renal function and urine parameters.
  • The specific effects of simple FC on kidney function in children require further investigation.

Purpose of the Study:

  • To evaluate renal function and urine analysis in children diagnosed with simple febrile convulsions.
  • To assess the prevalence of hematuria, proteinuria, and pyuria in children with FC.
  • To determine the impact of FC on estimated glomerular filtration rate (eGFR) and identify factors influencing kidney function changes.

Main Methods:

  • A cohort of 157 children with simple FC admitted to Amirkabir hospital between 2020-2021 were studied.
  • Kidney function was assessed using estimated glomerular filtration rate (eGFR).
  • Urinalysis, including tests for hematuria, proteinuria, and pyuria, and urine cultures were performed.

Main Results:

  • Hematuria, proteinuria, and pyuria were observed in 8.9%, 1.9%, and 5.1% of cases, respectively.
  • Two cases showed positive urine cultures, indicating infection.
  • A decrease in eGFR was noted in children with simple FC, irrespective of gender, with a more pronounced reduction in children over 24 months of age.

Conclusions:

  • Children experiencing febrile convulsions should undergo comprehensive renal function assessments.
  • Urinalysis and urine culture are recommended for children with FC to identify and manage potential urinary tract infections.
  • Early detection and management of renal alterations associated with FC are crucial for pediatric health.

Keywords:
febrile convulsionrenal functionurinalysisurinary tract infection

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