Related Experiment Video

Updated: Aug 18, 2025

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.5K

Incidence of Group B Streptococcus Disease in Infants in China: An Updated Systematic Review and Meta-analysis

Yijun Ding1, Yingfen Hsia2, Colleen O'Sullivan3

  • 1Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

The Pediatric Infectious Disease Journal
|December 8, 2022
PubMed

Insights

Group B Streptococcus (GBS) incidence in Chinese infants under three months has decreased to 0.41 cases per 1000 live births. This reduction may be linked to new intrapartum antibiotic prophylaxis policies.

Area of Science:

  • Neonatal infectious diseases
  • Epidemiology of bacterial infections
  • Public health interventions

Background:

  • Group B Streptococcus (GBS) remains a significant cause of neonatal infections.
  • Previous systematic reviews have established baseline incidence rates in infants.
  • Updated epidemiological data is crucial for assessing current disease burden and intervention effectiveness.

Approach:

  • Conducted a systematic review and meta-analysis of recent GBS studies in infants <3 months in China.
  • Employed the same rigorous methodology as previous reviews for consistent comparison.
  • Calculated updated incidence rates and confidence intervals.

Key Points:

  • The updated incidence of GBS in infants <3 months in China is 0.41 cases per 1000 live births (95% CI, 0.32-0.51).
  • This represents a decrease from the previously reported incidence of 0.55 per 1000 live births.
  • The implementation of new intrapartum antibiotic prophylaxis policies is a potential contributing factor to this observed reduction.

Conclusions:

  • Recent intrapartum antibiotic prophylaxis policies may have successfully reduced GBS incidence in neonates in China.
  • Continued surveillance and analysis are necessary to confirm the long-term impact of these public health strategies.
  • Findings provide valuable insights for global GBS prevention efforts.

More Related Videos

Probiotic Studies in Neonatal Mice Using Gavage10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.7K
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

1.4K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.1K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K