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Updated: Aug 18, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
benchdamic: benchmarking of differential abundance methods for microbiome data
Matteo Calgaro1, Chiara Romualdi2, Davide Risso3
1Department of Biotechnology, University of Verona, Verona 37134, Italy.
Summary:
Recently, an increasing number of methodological approaches have been proposed to tackle the complexity of metagenomics and microbiome data. In this scenario, reproducibility and replicability have become two critical issues, and the development of computational frameworks for the comparative evaluations of such methods is of utmost importance. Here, we present benchdamic, a Bioconductor package to benchmark methods for the identification of differentially abundant taxa.
Availability And Implementation:
benchdamic is available as an open-source R package through the Bioconductor project at https://bioconductor.org/packages/benchdamic/.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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