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Apgar scores correlate with survival rate at discharge in extremely preterm infants with gestational age of 25-27

Lili Lin1,2, Guosheng Liu1, Ying Li2

  • 1Department of Neonatology, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
|December 8, 2022
PubMed

Insights

The Apgar score, a measure of newborn health, is linked to survival in extremely preterm infants (gestational age 25-27 weeks). Higher scores generally correlate with better survival rates, though nuances exist for specific time points and gestational ages.

Area of Science:

  • Neonatal Medicine
  • Pediatrics
  • Perinatology

Background:

  • Low Apgar scores indicate higher mortality risk in newborns.
  • The Apgar score's utility in assessing extremely preterm infants remains debated.
  • Extremely preterm infants require specialized evaluation due to their vulnerability.

Purpose of the Study:

  • To characterize Apgar score distribution in extremely preterm infants (25-27 weeks gestation).
  • To investigate the association between Apgar scores and survival rates in this population.
  • To analyze clinical data from a large cohort of extremely preterm infants in China.

Main Methods:

  • Retrospective analysis of clinical data from 1567 extremely preterm infants.
  • Data collected from 26 neonatal intensive care units in Guangdong Province, China (2008-2017).
  • Statistical analysis of Apgar scores (1, 5, and 10 min) in relation to gestational age, birth weight, and survival to discharge.

Main Results:

  • Apgar scores increased with gestational age (25-27 weeks) and post-birth time (1-10 min).
  • Higher Apgar scores were associated with increased survival rates.
  • No significant association was found between 1-min Apgar and survival for 25-26 week infants, nor 5-min Apgar for 25-week infants.

Conclusions:

  • Apgar scores are associated with survival outcomes in extremely preterm infants.
  • The predictive value of Apgar scores may vary based on gestational age and time point.
  • Further research is needed to refine the use of Apgar scores in extremely preterm neonates.

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