Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epigenetic Regulation01:46

Epigenetic Regulation

31.3K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
31.3K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

34.9K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.9K
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

6.4K
Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
6.4K
Nucleosome Remodeling02:54

Nucleosome Remodeling

9.3K
Nucleosomes are the basic units of chromatin compaction. Each nucleosome consists of the DNA bound tightly around a histone core, which makes the DNA inaccessible to DNA binding proteins such as DNA polymerase and RNA polymerase. Hence, the fundamental problem is to ensure access to DNA when appropriate, despite the compact and protective chromatin structure.
Nucleosome remodeling complex
Eukaryotic cells have specialized enzymes called ATP-dependent nucleosome remodeling enzymes. These enzymes...
9.3K
Heterochromatin02:38

Heterochromatin

14.1K
The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions that take up more dye are called heterochromatin. Heterochromatin is further classified into two forms – constitutive heterochromatin and facultative heterochromatin.
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at...
14.1K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

7.9K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-omics analysis provides genetic evidence for the involvement of cell adhesion pathway in the pathogenesis of biliary atresia.

Science China. Life sciences·2026
Same author

Genetic and epigenetic mechanisms underlying male reproductive thermotolerance.

Current opinion in plant biology·2026
Same author

Educational standards for Australian social prescribing link workers: a modified Delphi study.

Frontiers in public health·2026
Same author

Excitation-wavelength-dependent emission of a luminescent host-guest Zn(II) metal-organic framework for high-performance white LEDs.

Chemical communications (Cambridge, England)·2026
Same author

Growing Inequities in Median Age of Death and Obesity Prevalence Between Australian Major Cities and Remote Areas: A National, Longitudinal, Spatial Analysis.

Public health challenges·2026
Same author

Characteristics of parks associated with depression in women only: a cross-sectional study of 329,363 adults.

BMC medicine·2026

Related Experiment Video

Updated: Aug 18, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
09:42

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images

Published on: September 7, 2017

9.8K

DNA methylation dynamics during germline development.

Shengbo He1, Xiaoqi Feng2

  • 1Guangdong Laboratory for Lingnan Modern Agriculture, College of Agriculture, South China Agricultural University, Guangzhou, 510642, China.

Journal of Integrative Plant Biology
|December 8, 2022
PubMed
Summary

DNA methylation is crucial for plant development, particularly during sexual reproduction. Recent advances reveal dynamic DNA methylation changes in flowering plant germlines, controlling gene and transposon activity.

Keywords:
DNA methylationchromatinepigenetic reprogramminggermlinesmall interfering RNA

More Related Videos

Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina
07:50

Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina

Published on: August 29, 2018

9.0K
Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry
07:13

Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry

Published on: August 16, 2016

7.3K

Related Experiment Videos

Last Updated: Aug 18, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
09:42

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images

Published on: September 7, 2017

9.8K
Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina
07:50

Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina

Published on: August 29, 2018

9.0K
Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry
07:13

Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry

Published on: August 16, 2016

7.3K

Area of Science:

  • Epigenetics
  • Plant Developmental Biology

Background:

  • DNA methylation is vital for eukaryotic genome homeostasis and development in animals.
  • Research increasingly recognizes DNA methylation's role in plant development, especially during sexual reproduction.

Purpose of the Study:

  • To review recent advances in understanding DNA methylation dynamics during plant germline development.
  • To highlight functional methylation reprogramming events in flowering plant germlines.

Main Methods:

  • Whole-genome sequencing
  • Cell isolation techniques
  • Bioinformatics tools
  • Genetics, developmental biology, and cell biology approaches

Main Results:

  • Dynamic DNA methylation changes occur during germline development in flowering plants.
  • Methylation reprogramming events control gene and transposon activities in germlines.
  • Technological advances have enabled detailed study of these processes.

Conclusions:

  • DNA methylation dynamics are critical for successful sexual reproduction in flowering plants.
  • Understanding these epigenetic mechanisms is key to plant reproductive biology.