Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

2.3K
The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the...
2.3K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

2.8K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermal Post-Processing of 3D-Printed Poly(glycerol dodecanedioate) Controls Mechanics and Shape Memory Properties.

Polymer science & technology (Washington, D.C.)·2026
Same author

Age-associated B cells (ABCs) develop from a CNS-localized progenitor pool into a pro-inflammatory phenotype after stroke.

bioRxiv : the preprint server for biology·2026
Same author

Development of Alternate Stent Platforms for Pediatric and Congenital Applications.

Interventional cardiology clinics·2026
Same author

Quantitative photoacoustic tomography of skin vasculature predicts subcutaneous implant exposure.

Journal of biomedical optics·2026
Same author

Matching Polyjet 3D Printed Material Properties to Human Left Heart Tissue Mechanical Behavior.

Journal of biomedical materials research. Part B, Applied biomaterials·2025
Same author

Ultrasound-Guided Photoacoustic Monitoring of Vascular Ischemia in Implant-Induced Skin Necrosis.

Ultrasound in medicine & biology·2025

Related Experiment Video

Updated: Aug 18, 2025

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

12.7K

Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical

Harsha Ramaraju1, Annabel M McAtee1, Ryan E Akman1

  • 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
|December 8, 2022
PubMed
Summary

Biodegradable shape memory polymers (SMEs) like PGD are promising for regenerative medicine. Proper disinfection and sterilization methods, such as ethylene oxide at 37.8°C, are crucial to maintain material properties and ensure biocompatibility for clinical use.

Keywords:
biocompatibilityethylene oxideshape memory polymershelf-life

More Related Videos

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.1K
Electrospun Fibrous Scaffolds of Polyglycerol-dodecanedioate for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Polyglycerol-dodecanedioate for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

11.0K

Related Experiment Videos

Last Updated: Aug 18, 2025

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

12.7K
Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.1K
Electrospun Fibrous Scaffolds of Polyglycerol-dodecanedioate for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Polyglycerol-dodecanedioate for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

11.0K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Regenerative Medicine

Background:

  • Biodegradable shape memory polymers (SMEs) offer innovative solutions for minimally invasive surgeries in regenerative medicine.
  • Poly(glycerol dodecanedioate) (PGD), a biodegradable SME, exhibits properties suitable for soft tissue applications with transition temperatures near body temperature.
  • Ensuring the integrity of SMEs through effective disinfection and sterilization is critical for their clinical translation.

Purpose of the Study:

  • To evaluate the impact of various disinfection and sterilization methods on the physiochemical, thermomechanical, and shape recovery properties of PGD SMEs.
  • To assess the biocompatibility and endotoxin levels of PGD SMEs after undergoing different treatment protocols.
  • To establish optimal sterilization cycles for PGD-based biomedical devices for research and clinical applications.

Main Methods:

  • PGD SME samples were subjected to disinfection with 70% ethanol and UV254 nm irradiation.
  • Ethylene oxide (EtO) gas sterilization was performed at two different temperatures (37.8°C and 54.4°C).
  • Material properties (transition temperature, shape recovery), cytotoxicity (ISO-10993.5C), and endotoxin levels were evaluated post-treatment. Aging studies were also conducted.

Main Results:

  • Ethanol disinfection at 15 minutes and EtO sterilization at 54.4°C negatively impacted shape recovery rates and transition temperatures.
  • Aging significantly reduced shape recovery in EtO-sterilized samples.
  • EtO sterilization at 37.8°C demonstrated low cytotoxicity and acceptable endotoxin levels, comparable to controls, with good cell viability.
  • All tested disinfection/sterilization methods (Ethanol 1 min, UV 120 min, EtO 37.8°C, EtO 54.4°C) met FDA endotoxin limits for devices contacting blood/lymphatic tissues.

Conclusions:

  • Disinfection with 70% ethanol for short durations (0.5-1 min) and UV irradiation preserve PGD SME properties for research.
  • Ethylene oxide sterilization at 37.8°C is a viable method for clinical applications, maintaining biocompatibility and acceptable endotoxin levels.
  • Optimized sterilization cycles are essential for the successful translation of PGD-based biodegradable SMEs in regenerative medicine and minimally invasive surgery.