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Bone Age Evaluated With Conventional Ultrasound: The Inter-Side Difference.

Ying Zhao¹, Jie Wan², Pin Lv¹

¹Department of Medical Ultrasound, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine

|December 8, 2022

Summary

Ultrasound bone age assessment shows inter-side differences, particularly in girls, indicating both left and right sides should be evaluated for accurate clinical assessment. This study confirms ultrasound

Keywords:

bone age inter-side difference ultrasound

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Area of Science:

Pediatric radiology
Skeletal imaging
Diagnostic ultrasound

Background:

Bone age assessment is crucial for evaluating growth and development in children.
Conventional methods like radiography have limitations and radiation exposure concerns.
Ultrasound offers a non-invasive alternative for bone age evaluation.

Purpose of the Study:

To investigate the inter-side differences in bone age determined by conventional ultrasound.
To compare ultrasound-derived bone age with radiographic bone age.
To determine if both sides of the body should be assessed for bone age using ultrasound.

Main Methods:

Prospective study of 192 children (aged 3-15 years) undergoing bone age evaluation.
Ultrasound assessment of bone age using the summed ossification ratio of radius, ulna, and femur.
Radiographic bone age assessment using X-rays of the left hand and wrist for comparison.

Main Results:

Significant inter-side differences in ultrasonic bone age were observed, especially in girls (right side more advanced).
Differences between left and right ultrasonic bone age ranged from -0.89 to 0.67 years.
Ultrasound bone age showed variations compared to radiographic bone age, with differences ranging from -1.16 to 1.14 years.

Conclusions:

Clinically significant inter-side differences in bone age assessed by ultrasound are present, particularly in girls.
Both left and right sides should be evaluated using ultrasound for comprehensive bone age assessment.
Ultrasound provides a valuable, non-invasive method for bone age determination with consideration for side differences.