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Updated: Aug 18, 2025

Using Micro-Electro-Mechanical Systems MEMS to Develop Diagnostic Tools
Published on: October 1, 2007
Experimental and probabilistic model validation of ultrasonic MEMS transceiver for blood glucose sensing
Hara Prasada Tripathy1, Priyabrata Pattanaik1, Dilip Kumar Mishra1
1Semiconductor Research Laboratory, Faculty of Engineering and Technology (ITER), Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751030, India.
Abstract:
In contrast to traditional laboratory glucose monitoring, recent developments have focused on blood glucose self-monitoring and providing patients with a self-monitoring device. This paper proposes a system based on ultrasound principles for quantifying glucose levels in blood by conducting an in-vitro experiment with goat blood before human blood. The ultrasonic transceiver is powered by a frequency generator that operates at 40 kHz and 1.6 V, and variations in glucose level affect the ultrasonic transceiver readings. The RVM probabilistic model is used to determine the variation in glucose levels in a blood sample. Blood glucose levels are measured simultaneously using a commercial glucose metre for confirmation. The experimental data values proposed are highly correlated with commercial glucose metre readings. The proposed ultrasonic MEMS-based blood glucometer measures a glucose level of [Formula: see text] mg/dl. In the near future, the miniature version of the experimental model may be useful to human society.

