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Perspectives on the future of dysmorphology
Benjamin D Solomon1, Margaret P Adam2, Chin-To Fong3
1Medical Genetics Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.
American Journal of Medical Genetics. Part A
|December 9, 2022
Summary
Clinical genetics and genomics are rapidly advancing due to new technologies and artificial intelligence. Experts predict continued evolution in dysmorphology, the study of abnormal development, over the coming decades.
Area of Science:
- Clinical genetics and genomics
- Human developmental biology
- Medical research
Background:
- The field of clinical genetics has undergone significant transformation due to key milestones such as the human genome sequencing project.
- Advancements in sequencing technologies and the integration of artificial intelligence have revolutionized genetic research and clinical practice.
- Dysmorphology, the study of abnormal tissue form and development, has also been impacted by these technological and biomedical trends.
Discussion:
- The rapid evolution of clinical genetics and genomics necessitates a forward-looking perspective on dysmorphology.
- Technological progress and broader biomedical trends are reshaping the practice and scope of dysmorphology.
- Anticipating future directions requires input from diverse experts in the field.
Key Insights:
- The integration of artificial intelligence and advanced sequencing technologies is a major driver of change in clinical genetics.
- Dysmorphology is adapting to new tools and a broader understanding of developmental processes.
- Expert consensus highlights the inevitability of continued rapid change in the field.
Outlook:
- Future dysmorphology practice will likely involve more sophisticated genetic analysis and computational tools.
- Predicting the exact trajectory is challenging, but continuous innovation is expected.
- The field must prepare for ongoing evolution, integrating new insights into the study of abnormal development.
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