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Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
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Dynamic ST-segment elevation during head-up tilt test
Xianchao Jing1, Qingyong Chen1
1Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Summary
Dynamic ST-segment elevation during head-up tilt testing, even with normal coronary angiography, suggests non-coronary causes for this cardiac finding.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Head-up tilt testing (HUTT) is a diagnostic tool for syncope.
- ST-segment elevation on electrocardiogram (ECG) typically indicates myocardial ischemia.
Observation:
- This study observed dynamic ST-segment elevation during HUTT.
- Coronary angiography results were normal in these patients.
Findings:
- The observed ST-segment elevation during HUTT was not caused by coronary artery disease.
- This suggests an alternative mechanism for ECG changes during tilt testing.
Implications:
- Re-evaluates the diagnostic criteria for ST-segment elevation during tilt testing.
- Highlights the importance of considering non-ischemic causes for dynamic ST-segment changes in cardiology.
- May guide further research into the pathophysiology of HUTT-induced ECG abnormalities.

