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Updated: Aug 18, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
[How I explore... suspicion of insect venom allergy in children]
M Thimmesch1, M Fagnard1, M Iordachescu1,2
1r d'Allergologie, CHC MontLégia, Liège, Belgique.
Abstract:
Suspicion of allergy to insect venoms following bites (mosquito, bee, wasp, …) is a frequent reason for consultation in pediatric allergology. Very often, these are local or locoregional reactions, which do not justify any other additional examinations. Biological analyses are performed when desensitization is recommended. Preventive measures should be explained to the patient and his/her parents. Symptomatic treatment with antihistamine, alcohol swabs and local corticosteroids is prescribed for local or locoregional reactions. If the child has a history of generalized anaphylactic reaction, an emergency kit containing an antihistamine and two auto-injectable epinephrine pens should be prescribed. Desensitization is indicated in case of a severe anaphylactic reaction.
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