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Associations Between Attention Deficit Hyperactivity Disorder Symptom Dimensions and Disordered Eating Symptoms in
Zeynep Yilmaz1,2,3,4, Mary J Quattlebaum5, Pratiksha S Pawar6
1National Centre for Register-Based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark.
Behavior Genetics
|December 9, 2022
Summary
Shared genetics influence attention-deficit/hyperactivity disorder (ADHD) and disordered eating in adolescents. Understanding these links is crucial for developing targeted prevention and treatment strategies for both conditions.
Area of Science:
- Psychiatry
- Genetics
- Developmental Psychology
Background:
- Bivariate associations between attention-deficit/hyperactivity disorder (ADHD) and eating disorders are known in adolescents.
- The underlying mechanistic link between ADHD symptoms and disordered eating requires further investigation.
Purpose of the Study:
- To evaluate shared genetic and environmental influences on ADHD symptoms and disordered eating in adolescent twins.
- To elucidate the specific genetic and environmental pathways contributing to the comorbidity of ADHD and eating disorders.
Main Methods:
- Utilized bivariate models on a Swedish twin cohort (TCHAD) comprising 819 females and 756 males.
- Analyzed common additive genetic and unique environmental effects on ADHD symptoms and disordered eating.
Main Results:
- Common additive genetic and unique environmental factors largely explained the associations between ADHD and disordered eating.
- In girls, genetic factors significantly correlated cognitive/inattention problems with bulimia (0.54, 67% of phenotypic correlation).
- In boys, strong genetic correlations were found for conduct problems-bulimia (0.54, 83%) and hyperactivity-bulimia (0.54, 95%).
Conclusions:
- Shared genetic factors play a significant role in the comorbidity of ADHD and disordered eating in both sexes.
- Findings underscore the necessity for integrated preventative measures and specialized treatments addressing ADHD and disordered eating concurrently.
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