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Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
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Recurrence Rates for Pediatric Benign Ovarian Neoplasms.
Maria E Knaus1, Amanda J Onwuka2, Naila M Abouelseoud3
1Center for Surgical Outcomes Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio; Division of Pediatric Surgery, Department of Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Journal of Pediatric and Adolescent Gynecology
|December 10, 2022
Summary
Pediatric benign ovarian neoplasms recurred in 2.6% of cases. Mucinous cystadenomas showed a higher recurrence risk, and oophorectomy did not prevent recurrence in young females.
Area of Science:
- Pediatric Surgery
- Gynecologic Oncology
- Oncology
Background:
- Benign ovarian neoplasms are common in pediatric patients.
- Understanding recurrence patterns is crucial for optimal management.
Purpose of the Study:
- To determine the recurrence rates of pediatric benign ovarian neoplasms.
- To identify risk factors associated with recurrence.
Main Methods:
- Retrospective review of 426 females up to 21 years of age.
- Data collected from 8 pediatric hospitals (2010-2016).
- Analysis of primary operation details, follow-up imaging, and reoperation data.
Main Results:
- Overall recurrence rate was 2.6% (11 cases) with a median follow-up of 12.8 months.
- Mucinous cystadenomas had a significantly higher recurrence rate (10.5 per 100 person-months) compared to mature teratomas (0.4 per 100 person-months).
- Ovarian-sparing surgery versus oophorectomy did not impact recurrence rates.
Conclusions:
- Pediatric benign ovarian neoplasms have a low recurrence rate.
- Mucinous cystadenomas represent a higher-risk group for recurrence.
- Oophorectomy is not protective against recurrence in this population.
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