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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

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Autotransplantation with tooth replica: Technical note.

C Debortoli¹, F Afota¹, B Lerhe¹

¹Department of Oral and Maxillofacial Surgery, Head and Neck Institute, University Hospital of Nice, 30 Avenue Valombrose, 06100 Nice, France.

Journal of Stomatology, Oral and Maxillofacial Surgery

|December 10, 2022

Summary

This summary is machine-generated.

Dental autotransplantation using 3D-printed replicas is a viable surgical option for replacing missing teeth in children and adolescents. This technique offers a reliable solution for orthodontic-surgical treatment, showing promising results.

Keywords:

Autotransplantation Orthodontic surgery Tooth replica

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Last Updated: Aug 18, 2025

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Area of Science:

Oral and Maxillofacial Surgery
Orthodontics
Digital Dentistry

Background:

Dental autotransplantation replaces missing or injured teeth using undeveloped tooth roots.
Previous attempts at orthodontic traction were unsuccessful.
Digital technologies are advancing orthodontic-surgical treatments.

Purpose of the Study:

To evaluate the efficacy of dental autotransplantation using 3D-printed replicas.
To assess the outcomes of a double autotransplantation technique.

Main Methods:

Preoperative assessment with cone beam computed tomography (CBCT).
Double autotransplantation performed under general anesthesia.
Utilized 3D resin-printed dental replicas for surgical guidance.
Minimized extra-alveolar time to under 1 minute per tooth.

Main Results:

Pulp sensibility was observed 3 months post-transplantation.
Successful implantation of two canines was achieved.

Conclusions:

Dental autotransplantation with 3D-printed replicas is a reliable and reproducible therapeutic solution.
This digital approach offers an advantageous benefit/risk balance for children and adolescents.
It is an essential orthodontic-surgical treatment for dental agenesis or non-preservable teeth.