Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

16
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
16
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

24
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
24
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

19
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
19
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

827
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
827
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

25
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
25

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uterine contractile activity thresholds associated with neonatal acidemia at term: A secondary analysis of a randomized controlled trial cohort.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026
Same author

Analgesic nonresponsiveness to nitrous oxide during labour as a risk factor for postpartum depression: a prospective observational cohort study.

British journal of anaesthesia·2026
Same author

The Effect of Metformin on Insulin Requirement, Glycaemic Control and Weight Gain in Type 1 Diabetes During Pregnancy-a Randomised, Placebo-Controlled Multicentre Study.

Diabetes/metabolism research and reviews·2025
Same author

Authors' Reply.

BJOG : an international journal of obstetrics and gynaecology·2025
Same author

Authors' Reply.

BJOG : an international journal of obstetrics and gynaecology·2025
Same author

Primiparous and multiparous women's birthing experiences and satisfaction with pain management in the first and second stages of vaginal delivery-A prospective cohort study.

Acta obstetricia et gynecologica Scandinavica·2025

Related Experiment Video

Updated: Aug 18, 2025

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.0K

Thromboelastometry-guided treatment algorithm in postpartum haemorrhage: a randomised, controlled pilot trial.

Samuli Jokinen1, Anne Kuitunen2, Jukka Uotila3

  • 1Department of Emergency Medicine, Pain Medicine and Anaesthesiology, Tampere University Hospital, Tampere, Finland.

British Journal of Anaesthesia
|December 10, 2022
PubMed
Summary

Rotational thromboelastometry (ROTEM)-guided postpartum hemorrhage treatment may reduce plasma product use. This randomized trial found ROTEM guidance showed a plasma-sparing effect but minimal impact on overall blood loss.

Keywords:
coagulopathyfibrinogenmassive haemorrhage protocolobstetric anaesthesiapostpartum haemorrhagethromboelastometrytransfusion

More Related Videos

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
07:50

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

Published on: June 4, 2021

2.8K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.1K

Related Experiment Videos

Last Updated: Aug 18, 2025

Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

22.0K
An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
07:50

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

Published on: June 4, 2021

2.8K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.1K

Area of Science:

  • Obstetrics and Gynecology
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Postpartum hemorrhage (PPH) is a leading cause of maternal mortality.
  • Conventional coagulation testing and clinical judgment guide PPH management.
  • Rotational thromboelastometry (ROTEM) offers a potential for goal-directed coagulation therapy in PPH.

Purpose of the Study:

  • To compare ROTEM-guided therapy versus conventional management for PPH.
  • To determine if ROTEM guidance reduces the need for red blood cell (RBC) transfusion in PPH.

Main Methods:

  • A parallel-design, randomized controlled trial was conducted.
  • Sixty parturients with PPH exceeding 1500 ml were randomized.
  • The primary outcome was blood product consumption; secondary outcomes included thromboembolic complications, infections, and transfusion reactions.

Main Results:

  • The median RBC units transfused were 2 in the ROTEM group versus 3 in the control group (P=0.399).
  • A significant difference in OctaplasLG® units was observed (median 0 vs. 0-2, P=0.030), indicating a plasma-sparing effect.
  • Median total estimated blood loss was lower in the ROTEM group (2500 ml) compared to the control group (3000 ml) (P=0.033).

Conclusions:

  • ROTEM-guided PPH treatment may offer a plasma-sparing benefit.
  • The reduction in total blood loss with ROTEM guidance appears to be small.
  • Further research may be needed to fully elucidate the benefits of ROTEM in PPH management.