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Updated: Aug 18, 2025

Transcranial Pulse Stimulation for Alzheimer's Patients
Published on: April 4, 2025
Long-Term Multi-Sensory Gamma Stimulation of Dementia Patients: A Case Series Report
Amy Clements-Cortes1, Lee Bartel1
1Faculty of Music, St. George Campus, University of Toronto, 80 Queens Park, Toronto, ON M5S 2C5, Canada.
Abstract:
Dementia prevalence is increasing globally, and symptom management and treatment strategies require further investigation. Music-based interventions have demonstrated some efficacy with respect to quality of life and symptom reduction, though limited with respect to cognition. This study reports on three case studies where the use of gamma stimulation over one year contributed to maintenance of cognition and increases in mood for participants with Alzheimer's disease or mild cognitive impairment. Auditory stimulation with isochronous sound at 40 Hz was delivered to participants via a commercially available vibroacoustic chair device five times per week for 30 min with assistance from caregivers. Further research is needed to assess the integration of this therapy in the overall care for persons with dementia.
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