Related Experiment Video
Updated: Aug 18, 2025
07:54
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
6.9K
Asbestos Exposure and Severity of COVID-19
Galo Granados1,2,3, María Sáez-López1, Cristina Aljama1
1Department of Respiratory Medicine, Vall d'Hebron University Hospital, Passeig Vall d'Hebron, 119-129, 08035 Barcelona, Spain.
International Journal of Environmental Research and Public Health
|December 11, 2022
Summary
Occupational asbestos exposure was linked to more severe COVID-19 pneumonia requiring respiratory support. However, this association was not confirmed independently in multivariate analysis for asbestos and COVID-19 severity.
Area of Science:
- Occupational Health
- Infectious Diseases
- Pulmonology
Background:
- Investigating the impact of occupational exposures on infectious disease outcomes.
- Understanding potential risk factors for severe SARS-CoV-2 infection.
Purpose of the Study:
- To analyze the relationship between occupational asbestos exposure and the severity of SARS-CoV-2 infection (COVID-19).
Main Methods:
- Evaluated surviving COVID-19 pneumonia patients.
- Collected demographic, clinical, and analytical data.
- Administered asbestos exposure questionnaire, spirometry, CO diffusion, 6-min walk test, and CT scans.
- Defined severe COVID-19 as requiring respiratory support.
Main Results:
- 293 patients included; 24% had occupational asbestos exposure.
- Asbestos-exposed patients showed higher rates of severe COVID-19 requiring respiratory support (77.6% vs. 61.5%).
- Univariate analysis showed an association, but multivariate analysis did not confirm independent links between asbestos exposure and COVID-19 severity or long-term lung function.
Conclusions:
- Occupational asbestos exposure was associated with increased need for respiratory support in hospitalized COVID-19 patients.
- An independent association between asbestos exposure and COVID-19 severity was not confirmed.
- No differences in follow-up lung function tests or CT findings were observed between exposed and unexposed groups.
Related Concept Videos
01:29Pulmonary Tuberculosis I
297
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
297
01:24Asthma-III: Symptoms and Complications
2.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.6K
01:29Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
01:20COPD: Pathogenesis and Clinical Features
430
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
430
01:17Other Pulmonary Disorders
890
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
890
01:26Asthma-II: Pathophysiology and Classification
2.8K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.8K