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Related Experiment Video

Updated: Aug 18, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
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A Simple Repair Algorithm for Descemet's Membrane Detachment Performed at the Slit Lamp.

Fan Li1, Zhe Zhu2, Lubo Fan1

  • 1Eye Center, Zhongshan City People's Hospital, Zhongshan 528403, China.

Journal of Clinical Medicine
|December 11, 2022
PubMed
Summary
This summary is machine-generated.

A simplified algorithm effectively repaired Descemet

Keywords:
Descemet’s membrane detachmentPentacamanterior segment optical coherence tomographycorneal edemaphacoemulsificationslit lamp

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Anterior Segment Surgery

Background:

  • Descemet's membrane detachment (DMD) can cause persistent corneal edema after phacoemulsification.
  • Conservative treatments are often ineffective for significant DMD.

Purpose of the Study:

  • To investigate a simple, safe, and effective repair algorithm for Descemet's membrane detachment (DMD).
  • To evaluate the efficacy of Pentacam and anterior segment optical coherence tomography (AS-OCT) in delineating DMD.
  • To assess visual outcomes and complications following the repair procedure.

Main Methods:

  • Retrospective study of 12 patients with persistent corneal edema due to DMD.
  • Delineation of DMD using Pentacam and AS-OCT.
  • Repair involved paracentesis and intracameral air injection, followed by supine positioning.
  • Outcomes assessed included DM reattachment, visual acuity, and complications at one month.

Main Results:

  • Complete reattachment of Descemet's membrane and corneal clarity were achieved in all 12 eyes.
  • 91.7% of eyes required only one repair procedure.
  • No major adverse events were recorded; one eye experienced temporary increased intraocular pressure.

Conclusions:

  • A simplified, outpatient repair algorithm for DMD, guided by Pentacam and AS-OCT, is safe and effective.
  • This approach facilitates timely diagnosis, evaluation, and management of DMD.
  • The algorithm shows promise for improving visual outcomes in patients with post-phacoemulsification DMD.