Related Experiment Video
Updated: Aug 18, 2025

07:37
Transpupillary-Guided Trans-Scleral Transplantation of Subretinal Grafts in a Retinal Degeneration Mouse Model
Published on: January 26, 2024
1.4K
Sandwich (Amnion/Conjunctival-Limbal Autograft/Amnion) Transplantation for Recurrent Pterygium with Restrictive
Hang Wong1, Jia-Song Wang1, Ya-Li Du1
1Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Journal of Clinical Medicine
|December 11, 2022
Summary
Sandwich transplantation effectively treats recurrent pterygium with restrictive strabismus. This procedure restored ocular motility and corrected esotropia without complications in all patients.
Area of Science:
- Ophthalmology
- Ophthalmic Surgery
Background:
- Recurrent pterygium can lead to restrictive strabismus, impacting ocular motility and visual function.
- Previous pterygium excision surgeries may not fully address associated motility issues.
Purpose of the Study:
- To evaluate the clinical outcomes of Sandwich (Amnion/Conjunctival-Limbal Autograft/Amnion) transplantation for recurrent pterygium with restrictive strabismus.
- To assess the safety and efficacy of this surgical technique.
Main Methods:
- Retrospective analysis of 11 eyes from 11 patients with recurrent pterygium and restrictive strabismus.
- Patients underwent Sandwich transplantation, and outcomes were measured by pterygium recurrence, visual acuity, esotropia correction (prism diopters), and complications.
Main Results:
- All patients achieved orthotropia post-surgery, with corrected esotropia and restored ocular motility.
- Symblepharon was resolved in all cases, and no significant complications like donor site scarring, scleral melt, or corneal ulcers were observed.
- The mean follow-up was 19.9 months, with patients having a history of 1.8 prior pterygium surgeries.
Conclusions:
- Sandwich transplantation is a safe and effective surgical option for recurrent pterygium with restrictive strabismus.
- The procedure successfully addresses both the pterygium recurrence and the associated motility deficits.

