Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Colloidal Gold Dietary Supplements as Nanomaterials: Physicochemical Evaluation, Estimated Oral Exposure, and Preliminary Biological Assessment.

International journal of molecular sciences·2026
Same author

Congo Red-Functionalized Maize Stalk for Fe<sup>3+</sup>, Cr<sup>3+</sup> and Mn<sup>2+</sup> Adsorption: Multi-Analytical Characterization of Interaction Mechanisms.

Polymers·2026
Same author

AgNPs-Cellulose Nanofiber/Polyacrylamide Hydrogels as an Antibacterial Platform for Soft Tissue.

Gels (Basel, Switzerland)·2026
Same author

Adsorption-Based Mitigation of Azo Dye Toxicity: Removal of Direct Red 23 Using Amberlite XAD-4 Resin.

Toxics·2026
Same author

Dual <i>Arnica montana</i> and <i>Ruscus aculeatus</i> Hyaluronic Acid-Modified Nanostructured Lipid Carriers for Accelerated Wound Healing Effect.

Antioxidants (Basel, Switzerland)·2026
Same author

Antibacterial Packaging for Cheese Based on Carboxymethyl Cellulose Composite with Zinc Oxide and Thyme Essential Oil.

Foods (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jun 24, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.2K

MAPLE Processed Nanostructures for Antimicrobial Coatings.

Ariana Hudiță1, Valentina Grumezescu2, Oana Gherasim2

  • 1Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania.

International Journal of Molecular Sciences
|December 11, 2022
PubMed
Summary

This study optimized silica-coated magnetite nanoparticles with eugenol as a bioactive coating for medical devices. The novel nanocoatings demonstrate superior biocompatibility and antimicrobial properties, reducing biofilm risks.

Keywords:
APTMSMAPLEantibiofilmeugenolmagnetite

More Related Videos

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

3.2K
Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils
07:47

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Published on: April 7, 2023

8.1K

Related Experiment Videos

Last Updated: Jun 24, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.2K
Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

3.2K
Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils
07:47

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Published on: April 7, 2023

8.1K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Antimicrobial Research

Background:

  • Indwelling medical devices are susceptible to microbial colonization and biofilm formation.
  • Biofilms exhibit high resistance to antibiotics and host defenses, leading to complications.
  • There is a need for advanced coatings to prevent device-related infections.

Purpose of the Study:

  • To optimize a silica (SiO2)-coated magnetite (Fe3O4)-based nanosystem containing eugenol (E) for bioactive coatings.
  • To evaluate the nanosystem's suitability for matrix-assisted pulsed laser evaporation (MAPLE) deposition.
  • To assess the biocompatibility and antimicrobial efficacy of the developed nanocoatings.

Main Methods:

  • Characterization of nanosystems using X-ray diffraction, thermogravimetric analysis, FTIR, and transmission electron microscopy.
  • In vitro assessment of nanocoating biocompatibility with dermal fibroblasts.
  • Evaluation of nanocoatings' effect on human blood samples to detect proinflammatory responses.

Main Results:

  • The Fe3O4@SiO2 nanosystems demonstrated superior biocompatibility, supporting dermal fibroblast viability and proliferation.
  • The nanocoatings showed no cytotoxic activity and sustained normal cellular development.
  • No proinflammatory events were induced in human blood samples, indicating a lack of proinflammatory potential.
  • Magnetite nanoparticles enhanced eugenol's antimicrobial activity, while the silica matrix prolonged its efficacy.

Conclusions:

  • Optimized Fe3O4@SiO2 nanosystems with eugenol offer a promising bioactive coating for biomedical applications.
  • These nanocoatings exhibit excellent biocompatibility and antimicrobial properties, reducing infection risks associated with medical devices.
  • The developed MAPLE-compatible nanocoatings represent a significant advancement in preventing biofilm formation and improving patient outcomes.