Related Experiment Video
Updated: Jul 26, 2026

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
Published on: May 24, 2017
Peculiarities of Scattering of Ultrashort Laser Pulses on DNA and RNA Trinucleotides
Dmitry Makarov1, Anastasia Kharlamova1
1Department of Fundamental and Applied Physics, Northern (Arctic) Federal University, Nab. Severnoi Dviny 17, 163002 Arkhangelsk, Russia.
Abstract:
Currently, X-ray diffraction analysis (XRD) with high spatial and time resolution (TR-XRD) is based on the known theory of X-ray scattering, where the main parameter of USP-its duration-is not taken into account. In the present work, it is shown that, for scattering of attosecond USPs on DNA and RNA trinucleotides, the pulse length is the most important scattering parameter. The diffraction pattern changes considerably in comparison with the previously known scattering theory. The obtained results are extremely important in TR-XRD when using attosecond pulses to study trinucleotides of DNA and RNA, because with the previously known scattering theory, which does not take into account the duration of USP, one cannot correctly interpret, and therefore "decode", DNA and RNA structures.

