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[Bacteriological study of acute otitis media in children. Therapeutic consequences]
Insights
This study identified common bacteria in childhood acute otitis media, finding Streptococcus pneumoniae and Haemophilus influenzae most prevalent. Antibiotic resistance was noted, particularly erythromycin and cotrimoxazole resistance in key pathogens.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Abstract:
One hundred children presenting with acute otitis media underwent a bacteriological study of otitis exudate over a 18 month period. The bacteria found were as follows: Streptococcus pneumoniae (24), Haemophilus influenzae (19), Staphylococcus aureus (12), Streptococcus pyogenes (7), Branhamella catarrhalis (3), and 18 Gram negative bacilli (including 7 Pseudomonas aeruginosa and 11 enterobacteriaceae). One pathogenic bacterium was isolated in 56 cases, 2 or more in 12 cases and none in 32 cases. In the age categories 0-1 year (47 cases) and 1-3 years (31 cases), S. pneumoniae and H. influenzae were the main organisms found, followed by S. pyogenes in children older than 3 years (22 cases). With respect to the antibiotics used for treating otitis, 5/22 S. pneumoniae and 4/17 H. influenzae were erythromycin resistant (9/17 had an intermediate susceptibility) and 7/19 H. influenzae and 1/17 S. pneumoniae were cotrimoxazole resistant. None of the S. pneumoniae and 2/19 H. influenzae were ampicillin resistant. These 2 H. influenzae and 2/3 B. catarrhalis were beta-lactamase producers. They were sensitive to the combination of amoxicillin with clavulanic acid.