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Positive FDG-PET/CT uptake guiding diagnosis in a patient with microscopic polyangiitis: A case report
Napisa Bunnag1,2, Kitwiwat Phuangmali2,3,4, Sira Vachatimanont2,3
1Department of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Abstract:
Microscopic polyangiits (MPA) is an autoimmune vasculitis that is challenging to diagnose because it can present with myriad of manifestations. We present a case of a woman who presented with prolonged fever. Her diagnosis of MPA was realized after fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG-PET/CT) showed abnormal diffuse renal uptake in the cortex, leading to a kidney biopsy. Our report supported the value of FDG-PET/CT as a diagnostic tool in a patient with febrile illness without localizing symptoms or signs.
Insights
Microscopic polyangiitis (MPA), an autoimmune vasculitis, can be difficult to diagnose. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG-PET/CT) aided in diagnosing MPA in a patient with prolonged fever and non-specific symptoms.
Area of Science:
- Immunology
- Radiology
- Nephrology
Background:
- Microscopic polyangiitis (MPA) is a rare autoimmune vasculitis.
- MPA diagnosis is often delayed due to diverse and non-specific clinical presentations.
- Prolonged fever without localizing signs can be a challenging initial symptom.
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