Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Issues And Trends In Healthcare Delivery System

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

Non-equilibrium in the Cell

Non-equilibrium in the Cell

An important concept in studying metabolism and energy is that of chemical equilibrium. Most chemical reactions are reversible. They can proceed in both directions, releasing energy into their environment in one direction, and absorbing it from the environment in the other direction. The same is true for the chemical reactions involved in cell metabolism, such as the breaking down and building up of proteins into and from individual amino acids, respectively. Reactants within a closed system...

Plant Breeding and Biotechnology

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.

Microorganisms in Medicine and Therapeutics

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

Hybridoma Technology

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Metabolite-based cell sorting workflow for identifying microbes producing carbonyls in tobacco leaves.

Applied microbiology and biotechnology·2022

Same author

High-Level 5-Methyltetrahydrofolate Bioproduction in <i>Bacillus subtilis</i> by Combining Modular Engineering and Transcriptomics-Guided Global Metabolic Regulation.

Journal of agricultural and food chemistry·2022

Same author

Improved Productivity of <i>Streptomyces mobaraensis</i> Transglutaminase by Regulating Zymogen Activation.

Frontiers in bioengineering and biotechnology·2022

Same author

Active secretion of a thermostable transglutaminase variant in Escherichia coli.

Microbial cell factories·2022

Same author

Combining CRISPR-Cpf1 and Recombineering Facilitates Fast and Efficient Genome Editing in <i>Escherichia coli</i>.

ACS synthetic biology·2022

Same author

Vitamin C enhances the <i>ex vivo</i> proliferation of porcine muscle stem cells for cultured meat production.

Food & function·2022

Search research articles

Related Experiment Video

Updated: Aug 17, 2025

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Artificial intelligence technologies in bioprocess: Opportunities and challenges.

Yang Cheng¹, Xinyu Bi¹, Yameng Xu¹

¹Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Science Center for Future Foods, Ministry of Education, Jiangnan University, Wuxi 214122, China.

Bioresource Technology

|December 12, 2022

Summary

Artificial intelligence (AI) enhances bioprocess control and optimization by integrating data-driven modeling and rapid detection technologies. This review guides future development of AI-guided bioprocess optimization and control for improved microbial metabolic potential.

Keywords:

Artificial intelligence Bioprocess modeling Rapid detection Real-time monitoring Smart control

More Related Videos

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Published on: May 18, 2020

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Published on: September 28, 2018

Related Experiment Videos

Last Updated: Aug 17, 2025

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Published on: May 18, 2020

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Published on: September 28, 2018

Area of Science:

Biotechnology and biochemical engineering
Process systems engineering
Microbial biotechnology

Background:

Bioprocess control and optimization are essential for maximizing microbial metabolic potential.
Advancements in computer-based strategies combined with current technologies promise significant bioprocess improvements.
Artificial intelligence (AI) offers a data-driven approach, independent of complex mathematical models, for bioprocess applications.

Approach:

This review discusses AI-guided modeling approaches for optimizing critical process parameters (CPPs) in bioprocesses.
It summarizes AI-assisted technologies for rapid detection and monitoring within bioprocesses.
The analysis includes control strategies derived from AI-guided modeling and monitoring.

Key Points:

AI-guided modeling optimizes critical process parameters (CPPs).
AI facilitates rapid detection and monitoring in bioprocesses.
Control strategies are analyzed based on AI-driven modeling and monitoring.

Conclusions:

AI integration offers a powerful pathway for advancing bioprocess optimization and control.
Future research should focus on addressing current gaps in AI-guided bioprocess technologies.
This review provides theoretical guidance for developing novel AI-guided bioprocess solutions.