Post-endoscopic submucosal dissection electrocoagulation syndrome: a clinical overview.

Area of Science:

• Gastroenterology
• Endoscopy
• Surgical Complications

Background:

• Post-endoscopic submucosal dissection electrocoagulation syndrome (PEECS) is a rare complication following endoscopic submucosal dissection (ESD).
• Current understanding and management of PEECS remain controversial, necessitating an updated review.
• This review aims to provide a comprehensive overview of PEECS.

Approach:

• A systematic search of the English-language literature was conducted.
• The review focused on pathogenesis, definition, diagnosis, incidence, risk factors, prevention, management, and prognosis of PEECS.
• Key aspects of PEECS were analyzed to consolidate current knowledge.

Key Points:

• Diagnostic criteria for PEECS are converging, typically involving localized abdominal tenderness and fever or inflammatory response without delayed perforation.
• While etiology and management remain debated, recent consensus exists on diagnostic criteria.
• Most patients diagnosed with PEECS exhibit a favorable prognosis with conservative management strategies.

Conclusions:

• PEECS is a recognized, albeit rare, complication of ESD.
• Consensus is growing on PEECS diagnostic criteria, aiding in timely identification.
• Conservative treatment generally leads to favorable outcomes, but further high-quality studies are required to address controversial aspects of PEECS.