Preparation of hydroxyethyl cellulose/ mangiferin edible films and their antimicrobial properties

Hebat-Allah S Tohamy1, Mohamed El-Sakhawy2, Hossam M El-Masry3

  • 1Cellulose and Paper Department, National Research Centre, 12622, Cairo, Egypt.

BMC Chemistry
|December 12, 2022
PubMed

Insights

Hydroxyethyl cellulose (HEC) films incorporated with mangiferin powder exhibit enhanced antimicrobial properties. The optimal concentration of 10% mangiferin powder significantly boosts the antimicrobial activity of HEC films for versatile applications.

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Biochemistry

Background:

  • Hydroxyethyl cellulose (HEC) is a versatile polymer with potential for film applications.
  • Mangiferin, a natural compound, possesses known antimicrobial properties.
  • Combining polymers and natural compounds can lead to synergistic effects in material properties.

Purpose of the Study:

  • To prepare and characterize antimicrobial films using hydroxyethyl cellulose (HEC) and mangiferin (M).
  • To investigate the effect of varying mangiferin concentrations on the antimicrobial efficacy and physical properties of HEC films.
  • To determine the optimal mangiferin concentration for enhanced antimicrobial activity.

Main Methods:

  • Preparation of HEC/M composite films with varying mangiferin concentrations (2.5, 5, 10% wt/vol).
  • Comprehensive analysis of film properties including physical, chemical, mechanical, and antimicrobial assessments.
  • Optimization of mangiferin concentration based on antimicrobial performance.

Main Results:

  • HEC/M films demonstrated enhanced antimicrobial activity compared to pure HEC.
  • Mangiferin powder imparted significant antimicrobial properties to the HEC matrix.
  • The optimal concentration for achieving maximum antimicrobial activity was found to be 10% (wt/vol) mangiferin.

Conclusions:

  • The developed HEC/M films show promising antimicrobial characteristics for various applications.
  • Mangiferin effectively enhances the antimicrobial capabilities of hydroxyethyl cellulose.
  • The study provides a foundation for utilizing natural compounds to create functional polymer films.

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