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Interventions for zoster-associated pain: A retrospective study based on the clinical database
1Department of Pain Management, West China Hospital, Sichuan University, Chengdu, China.
Frontiers in Neurology
|December 12, 2022
Summary
Interventions effectively reduced herpes zoster pain and improved quality of life. Advanced age, diabetes, and immune diseases are key risk factors for postherpetic neuralgia (PHN).
Area of Science:
- Pain Management
- Neurology
- Dermatology
Background:
- Herpes zoster (HZ)-associated pain significantly impacts patient quality of life.
- Effective treatment strategies and risk factor identification for zoster-associated pain are crucial.
Purpose of the Study:
- To evaluate the effectiveness of interventions for herpes zoster (HZ)-associated pain and postherpetic neuralgia (PHN).
- To identify risk factors associated with the development of PHN.
Main Methods:
- A study involving 131 patients with HZ and 230 with PHN.
- Interventions included nerve block, radiofrequency, and thermocoagulation.
- Pain assessed using Visual Analog Scale (VAS) and Brief Pain Inventory (BPI) scores over 12 months; logistic regression analyzed risk factors.
Main Results:
- Interventions significantly reduced VAS and BPI scores from baseline up to 12 months post-treatment.
- No significant differences in outcomes were observed based on pain duration or area.
- Advanced age, diabetes mellitus, and immune-related diseases were identified as significant risk factors for PHN.
Conclusions:
- Interventions provide significant relief from zoster-associated pain and improve quality of life, irrespective of pain duration or area.
- Identifying and managing risk factors like advanced age, diabetes, and immune conditions is vital for preventing PHN.
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