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Updated: Aug 17, 2025

Biological Preparation and Mechanical Technique for Determining Viscoelastic Properties of Zonular Fibers
Published on: December 16, 2021
A Forme Fruste of Marfan Syndrome: A Case Report
Nejood Alsheikh1, Samira A Hawsawi1, Abeer AlGhamdi1
1Medicine and Surgery, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Abstract:
Marfan syndrome (MFS), an inherited connective tissue disorder, is caused by a mutation in the FBN1 gene. MFS is characterized by manifestations in the musculoskeletal system (joint laxity, scoliosis), the cardiovascular system (aortic dilation), and the ocular system (ectopic lens). We report a case of a 37-year-old male with a genetically confirmed MFS. His mother and brother were also both confirmed cases of MFS. While the patient exhibited the characteristic physical features of MFS in general appearance, he did not show any cardiac manifestations of the disease. This report highlights a case of the familial occurrence of MFS and emphasizes the importance of recognizing the forme fruste of MFS.
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