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Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19

Agustín Valenzuela-Fernández1, Romina Cabrera-Rodriguez1, Laura Ciuffreda2

  • 1Laboratorio de Inmunología Celular y Viral, Unidad de Farmacología, Sección de Medicina, Facultad de Ciencias de la Salud, Universidad de La Laguna, San Cristóbal de La Laguna, Spain.

Frontiers in Bioengineering and Biotechnology
|December 12, 2022
PubMed

Insights

Nanotechnology offers innovative solutions for combating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19). Nano-based tools enhance prevention, diagnosis, and treatment, aiding in real-time surveillance and preparedness against evolving variants.

Area of Science:

  • Nanomedicine
  • Materials Science
  • Infectious Disease Research

Background:

  • The COVID-19 pandemic highlighted the urgent need for advanced medical countermeasures against SARS-CoV-2.
  • Traditional diagnostic and therapeutic approaches faced limitations in addressing the global health crisis.
  • Nanotechnology emerged as a critical field providing novel solutions for pandemic response.

Purpose of the Study:

  • To review the applications of nanotechnology in combating SARS-CoV-2 transmission, infection, and organ damage.
  • To explore nano-based materials for personal protective equipment and diagnostics.
  • To discuss the role of nanotechnology in developing vaccines and real-time virosurveillance.

Main Methods:

  • Review of scientific literature on nanotechnological applications for COVID-19.
  • Analysis of nano-based materials and their efficacy in prevention, diagnosis, and treatment.
  • Examination of nano-enabled vaccine development and epidemiological surveillance tools.

Main Results:

  • Nanotechnology has provided rapid, sensitive diagnostic tools and effective treatments for COVID-19.
  • Nano-based personal protective equipment offers enhanced protection against SARS-CoV-2.
  • Nano-enabled vaccines (e.g., mRNA) have been developed at unprecedented speed.
  • Real-time epidemiological surveillance and mutation tracking of SARS-CoV-2 have been significantly improved.

Conclusions:

  • Nanotechnology has been instrumental in the scientific response to the COVID-19 pandemic.
  • Nano-based strategies are crucial for preventing transmission, improving diagnostics, and developing effective treatments.
  • Continued advancements in nanotechnology are vital for preparedness against future viral threats and emerging variants.
Keywords:
genome sequencinglipid nanoparticlesmodified mRNAnanoreagentspersonal protective equipmentrecombinant proteinssurveillance and diagnosisvaccines

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