Related Experiment Video
Updated: Aug 17, 2025

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control
Anna Stoliaroff-Pepin1, Caroline Peine1, Tim Herath1
1Department for Infectious Disease Epidemiology, Immunization Unit, Robert Koch Institute, Germany.
Abstract:
We included 852 patients in a prospectively recruiting multicenter matched case-control study in Germany to assess vaccine effectiveness (VE) in preventing COVID-19-associated hospitalization during the Delta-variant dominance. The two-dose VE was 89 % (95 % CI 84-93 %) overall, 79 % in patients with more than two comorbidities and 77 % in adults aged 60-75 years. A third dose increased the VE to more than 93 % in all patient-subgroups.
Related Concept Videos
Vaccinations
Microorganisms in Medicine and Therapeutics

