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Lymphopenia during 177Lu-DOTATATE therapy leading to recurrence of tuberculosis: a case report
Sarah Boughdad1, Michael Da Mota2, Mélanie Mendes De Carvalho2
1Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland. sarah.boughdad@chuv.ch.
Abstract:
We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of 177Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesized that this recurrence might have been related to the occurrence of lymphopenia, which is common during PRRT. Indeed, though lymphopenia is frequently dismissed, it could lead to the development of opportunistic diseases and its severity should be examined, especially in case of abnormal clinical symptoms.
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