Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

25
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
25
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

28
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
28
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

29
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
29
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

16
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
16
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

36
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
36
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

25
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
25

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intercostal Electromyographic Responses to Multi-Site Chest Wall Vibration at an Optimal Frequency.

Respiratory physiology & neurobiology·2026
Same author

Urgent Resection of Hepatocellular Carcinoma With Intracardiac Extension Under Moderate Hypothermic Circulatory Arrest.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Transcatheter aortic valve replacement use in young patients before and after the first low-risk trial publication.

JTCVS structural and endovascular·2026
Same author

Weather-related triggers of acute aortic dissection: a case-crossover study of 293 patients.

General thoracic and cardiovascular surgery·2026
Same author

Emergence of norovirus GII.7 and predominance of recombinant strains in pediatric acute gastroenteritis in Japan, 2021-2024.

Archives of virology·2026
Same author

Co-Circulation and Mixed Infections of Classic and Melbourne Human Astroviruses Among Pediatric Acute Gastroenteritis Patients in Japan, 2018-2024.

Journal of medical virology·2026

Related Experiment Video

Updated: Aug 17, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.7K

Midterm results after seamless patch mitral reconstruction.

Soh Hosoba1, Toshiaki Ito1, Makoto Mori2

  • 1Department of Cardiovascular Surgery, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.

JTCVS Techniques
|December 13, 2022
PubMed
Summary

Mitral valve repair using a seamless pericardial patch shows excellent midterm outcomes for certain leaflet conditions. This technique is most effective for commissural lesions or up to two leaflet segments, avoiding conversion to valve replacement.

Keywords:
MR, mitral regurgitationMS, mitral stenosisSRT, seamless patch reconstruction techniqueautologous pericardiummitral valvemitral valve reconstructionmitral valve repair

More Related Videos

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.0K
Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

404

Related Experiment Videos

Last Updated: Aug 17, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.7K
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.0K
Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

404

Area of Science:

  • Cardiovascular Surgery
  • Biomaterials in Medicine
  • Surgical Techniques

Background:

  • Conventional mitral valve repair is challenging for pathologies like infective endocarditis or leaflet sclerosis.
  • A seamless pericardial patch technique has been developed for complex mitral valve reconstructions.
  • The safe extent of leaflet repair using this patch technique requires further investigation.

Purpose of the Study:

  • To investigate the midterm outcomes of mitral valve repair using a seamless pericardial patch.
  • To determine the association between the extent of mitral leaflet segments repaired and the midterm clinical outcomes.

Main Methods:

  • A retrospective study included 49 patients undergoing mitral valve repair with a seamless 1-patch technique between January 2009 and January 2022.
  • The technique involves using a glutaraldehyde-treated pericardial patch anchored to the papillary muscle and sutured to the leaflet and annulus.
  • A totally endoscopic approach was utilized in 55% of cases.

Main Results:

  • No operative mortality or disabling stroke occurred. Redo surgery was required in 18% of patients during midterm follow-up.
  • Freedom from mitral valve reintervention at 1, 5, and 10 years was 84%, 82%, and 82%, respectively.
  • Freedom from reoperation at 5 years was 100% for commissural lesions, 92% for 1-2 segment involvement, and 46% for 3-segment involvement (P=.002).

Conclusions:

  • Seamless pericardial patch reconstruction of the mitral valve yields excellent midterm results.
  • The technique is particularly effective for commissural lesions or lesions involving up to two leaflet segments.
  • Extensive leaflet repair (3 segments) is associated with a higher reoperation rate.