How to detect cancer early using cell-free DNA
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Updated: Oct 2, 2026

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Cell-Free DNA Integrity Analysis in Urine Samples
Published on: January 5, 2017
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Samantha O Hasenleithner1, Michael R Speicher2
1Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
Cancer Cell
|December 13, 2022
Abstract:
Cell-free circulating DNA (cfDNA) analyses may enable multi-cancer early detection (MCED), but the most suitable method is unknown. In this issue of Cancer Cell, Jamshidi et al. compare ten machine-learning classifiers using various cfDNA features and conclude that cfDNA methylation patterns are most promising for MCED testing.

