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Galactose tolerance in patients with atopic cataracts
M F Muhlemann1, J N Mount, J J Cream
1Department of Dermatology, Charing Cross Hospital, London, U.K.
The British Journal of Dermatology
|July 1, 1987
Summary
Galactose intolerance, or galactosaemia, does not appear to cause atopic cataracts in individuals with atopic dermatitis. A galactose tolerance test found normal results in most patients studied.
Area of Science:
- Ophthalmology
- Metabolic Disorders
- Dermatology
Background:
- Galactosaemia is a potential factor in developing certain types of cataracts.
- Atopic cataracts can manifest in young adults with atopic dermatitis.
Purpose of the Study:
- To investigate the potential role of galactosaemia in the pathogenesis of atopic cataracts.
- To determine if impaired galactose metabolism contributes to early-onset cataracts in atopic dermatitis patients.
Main Methods:
- A galactose tolerance test was administered to eight patients diagnosed with atopic dermatitis.
- Patients had cataracts that developed between the ages of 12 and 39 years.
Main Results:
- Seven out of eight patients exhibited normal galactose tolerance.
- One patient showed results slightly above the normal range, but not indicative of significant impairment.
Conclusions:
- Impaired galactose tolerance does not seem to be a significant factor in the development of atopic cataracts.
- The findings suggest that galactosaemia is unlikely to play a role in the pathogenesis of cataracts associated with atopic dermatitis.