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Updated: Aug 17, 2025

Roux-en-Y Gastric Bypass Operation in Rats
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Decrease phase angle one year after Roux-en-Y bypass and sleeve gastrectomy is related to risks to protein

A M Bortoli1, G B Braga1, B B Brito2

  • 1Postgraduate Program in Nutrition and Health (PPGNS), Health Sciences Center, Federal University of Espírito Santo, Marecal Campos Ave, 1468, Maruípe, Vitória-ES, 29040-090, Brazil.

Clinical Nutrition ESPEN
|December 13, 2022
PubMed
Summary
This summary is machine-generated.

Phase angle (PhA) reduction after bariatric surgery may signal declining protein status. Lower PhA correlates with reduced visceral protein and poorer nutritional outcomes one year post-surgery.

Keywords:
Bariatric surgeryGastrectomyGastric bypassNutritional statusObesity

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Area of Science:

  • Bariatric Surgery Outcomes
  • Nutritional Assessment
  • Biochemical Markers

Background:

  • Phase angle (PhA) is an established indicator of nutritional status.
  • The impact of bariatric surgery on PhA requires further investigation.
  • This study examines PhA changes following Roux-en-Y bypass (RYGB) and sleeve gastrectomy (SG).

Purpose of the Study:

  • To evaluate Phase angle (PhA) changes one year after bariatric surgery.
  • To assess the relationship between PhA and key biochemical markers.
  • To determine the correlation of PhA with prognostic inflammatory and nutritional indices post-surgery.

Main Methods:

  • Compared PhA, BMI, body composition, and serum markers (albumin, transthyretin) in RYGB and SG patients.
  • Collected data at baseline and at 2, 6, and 12 months post-operation.
  • Utilized ANOVA/Friedman tests and Spearman/Pearson correlations to analyze data.

Main Results:

  • Most parameters, except albumin, significantly decreased over one year (p < 0.001).
  • Transthyretin levels were below reference in the RYGB group.
  • PhA showed a significant positive correlation with transthyretin in both RYGB and SG groups (p < 0.001).

Conclusions:

  • Reduced Phase angle (PhA) post-bariatric surgery may indicate visceral protein loss.
  • Lower PhA values correlate with a worsening protein nutritional status.
  • PhA serves as a potential indicator for monitoring nutritional recovery after bariatric procedures.