Factor structure of the posttraumatic stress disorder checklist (PCL-17) in 279,897 million veteran program
Cassie Overstreet1, Daniel F Levey1, Hang Zhou1
1Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, Connecticut, United States.
Abstract:
The Million Veteran Program (MVP) uses the posttraumatic stress disorder symptoms (PTSD) Checklist 17 (PCL-17) self-report to assess PTSD. Existing literature suggests that the five-factor dysphoric arousal model best represents the PTSD symptom clusters; this can be tested within MVP, one of the largest samples collected with suitable data. We compared factor models within MVP across genetically defined subsamples (ancestry [European, African, admixed American, and East Asian], sex) via multi-group confirmatory factor analyses in a sample of 279,897 participants. The five-factor dysphoric arousal model best fit the PCL-17 data, consistent with previous findings. The factor structure could also be imposed across all groups tested. Verifying the factor structure provides a framework for future phenotypic and genotypic analyses within MVP and other samples.
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