Related Experiment Video
Updated: Aug 17, 2025

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
Published on: July 15, 2009
OsteoMacs and Their Role in Early Implant Failure and Osseointegration
Richard M Yang1, Huzefa S Talib2, Richard J Miron3
1Oral and Maxillofacial Surgery Resident, Highland Hospital Alameda Health System, Oakland, California.
Abstract:
Dental implant failure cannot always be explained by clinical risk factors. Recent literature suggests that immune cells are pivotal players in the integration of biomaterials and have a co-relationship within a set of osteal macrophages known as "OsteoMacs." These cells have been known to polarize quickly between a M1 pro-inflammatory and a M2 wound healing state during implant osseointegration. OsteoMacs play a critical immune surveillance role in the osseointegration of dental implant healing and bone homeostasis. This review is intended to provide an overview of the current understanding of OsteoMacs and their role in early implant failure and osseointegration.
Related Concept Videos
Osteoclasts in Bone Remodeling
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...

