Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clonidine. An effective anti-manic agent?

J Maguire1, A N Singh

  • 1St Brigid's Hospital, Ardee, Eire.

The British Journal of Psychiatry : the Journal of Mental Science
|June 1, 1987
PubMed
Summary
This summary is machine-generated.

Clonidine effectively treated three patients with treatment-resistant bipolar mania. This medication offers a rapid and safe alternative for managing manic episodes.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HPLC evaluation of storage and <i>Trichoderma</i> treatment effects on major flavonoids in <i>Oroxylum indicum</i> seeds.

Natural product research·2026
Same author

Development of an advanced analytical technique for detecting multiple pesticide residues in vegetables through liquid chromatography tandem mass spectroscopy (LC-MS/MS).

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes·2024
Same author

A new direction for tackling phosphorus inefficiency in the UK food system.

Journal of environmental management·2022
Same author

Drug-induced alopecia areata?

Clinical and experimental dermatology·2020
Same author

Management of humeral impending or pathological fractures with intramedullary nailing: reaming versus non reaming technique-a retrospective comparative study.

Musculoskeletal surgery·2020
Same author

Comparative litter decomposability traits of selected native and exotic woody species from an urban environment of north-western Siwalik region, India.

Scientific reports·2020

Area of Science:

  • Psychiatry
  • Neuropharmacology

Background:

  • Bipolar affective disorder, manic phase, presents significant treatment challenges.
  • Patients resistant to conventional therapies require novel therapeutic strategies.

Observation:

  • Three patients with treatment-resistant bipolar mania were administered clonidine.
  • The study observed the clinical response to clonidine in these patients.

Findings:

  • Clonidine demonstrated successful treatment outcomes in all three patients.
  • The rapid action and favorable side-effect profile of clonidine were noted.

Implications:

  • Findings support the nor-adrenergic hyperactivity theory of mania.
  • Clonidine presents a potential alternative anti-manic agent for clinical use.