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Infected nasal gout tophus: A case report.

Gill Verstappen¹, Olaf Michel¹, Stijn Halewyck¹

¹Department of Otorhinolaryngology - Head and Neck Surgery Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel Brussels Belgium.

Clinical Case Reports

|December 15, 2022

Summary

This summary is machine-generated.

Gout tophi, often developing from chronic inflammation, can now be found infected in the nasal septum and tip. This case highlights a rare presentation of infected gout tophi in a previously undocumented nasal location.

Keywords:

case report gout hyperuricemia tophus

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Area of Science:

Rheumatology
Infectious Diseases
Dermatology

Background:

Gout is a prevalent inflammatory arthritis caused by monosodium urate crystal deposition.
Chronic, undertreated gout can lead to the formation of tophi in various body locations.
Tophi are typically sterile, although secondary infection is possible.

Observation:

This report details the first documented instance of an infected gout tophus.
The infection was specifically located in the septal cartilage and nasal tip.
The tophus presented with signs of infection in this unusual anatomical site.

Findings:

The infected gout tophus in the nasal septum and tip represents a novel clinical finding.
This case expands the known anatomical distribution of infected gout tophi.
Microbial analysis confirmed the presence of infection within the urate crystal deposits.

Implications:

This case underscores the importance of considering infection in gout tophi, even in atypical locations.
Early diagnosis and appropriate treatment are crucial to manage infected tophi and prevent complications.
Further research is warranted to understand the pathogenesis and optimal management of infected gout tophi in diverse anatomical sites.