Related Experiment Video
Updated: Aug 17, 2025

Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
Published on: August 6, 2019
Anthranilamide-protected vinylboronic acid: rational monomer design for improved polymerization/transformation
Hiroshi Suzuki1, Tsuyoshi Nishikawa1, Hiroshi Makino1
1Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 606-8501 Japan nishikawa.tsuyoshi.8n@kyoto-u.ac.jp ouchi.makoto.2v@kyoto-u.ac.jp.
Abstract:
We have studied several protecting groups for vinylboronic-acid derivatives as monomers in radical polymerizations with the objective to improve the polymerization ability and C-B bond-cleaving post-transformation performance. Anthranilamide (aam)-protected vinylboronic acid (VBaam) exhibited experimentally a relatively high polymerization activity, which was theoretically corroborated by density functional theory (DFT) calculations that revealed a peculiar effect of the interaction between the aam groups on the polymerization behavior. The VBaam units in the copolymers can subsequently be transformed into vinyl alcohols or into ethylene units through C-B-bond-cleaving side-chain replacement, which affords valuable copolymers such as poly(vinyl alcohol-co-styrene), poly(ethylene-co-styrene), and poly(ethylene-co-acrylate).
More Related Videos
Related Concept Videos
Anionic Chain-Growth Polymerization: Overview
Ziegler–Natta Chain-Growth Polymerization: Overview
Characteristics and Nomenclature of Copolymers
Anionic Chain-Growth Polymerization: Mechanism
Polymer Classification: Stereospecificity
Cationic Chain-Growth Polymerization: Mechanism

