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Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function

Wonyul Jang1, Dmytro Puchkov1, Paula Samsó1

  • 1Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.

Science (New York, N.Y.)
|December 15, 2022
PubMed
Summary

MTM1 regulates cell adaptation to nutrient changes by controlling endosomal signaling. This impacts endoplasmic reticulum shape, mitochondrial function, and metabolism during starvation.

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