Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanisms of Membrane Domain Formation

Mechanisms of Membrane Domain Formation

Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Machine-learning accelerated density-explicit polymer field theory simulations.

The Journal of chemical physics·2026

Same author

Molecular understanding of ion transport in a zwitterionic electrolyte.

The Journal of chemical physics·2025

Same author

Coherent state field theory: A tool for inhomogeneous polymer dynamics and rheology.

The Journal of chemical physics·2025

Same author

Molecularly informed field-theoretic models of confined fluids.

The Journal of chemical physics·2025

Same author

Efficient dynamical field-theoretic simulations for multi-component systems.

The Journal of chemical physics·2025

Same author

Preserving positivity in density-explicit field-theoretic simulations.

The Journal of chemical physics·2024

Same journal

Multitargeted Degradation of Cell Surface Receptors by Modular Glyco-Nanosheets.

ACS macro letters·2026

Same journal

Vinyl Ether Maleic Anhydride Copolymers: Efficient and Reusable Sorbents for Removing Heavy Metals from Water.

ACS macro letters·2026

Same journal

Topology-Preserving Elastic Deformation Augmentation Enables Robust Defect Detection in Data-Scarce Industrial Imagery.

ACS macro letters·2026

Same journal

Flexible Porous Organic Polymers with α,β-Enone-Linkage via AlCl<sub>3</sub>-Catalyzed Horner-Wadsworth-Emmons Polymerization for Pd Recovery.

ACS macro letters·2026

Same journal

Light-Controlled Topology Switching Enables Continuous Modulation of Thermally Induced Phase Behavior in Polymer Solutions.

ACS macro letters·2026

Same journal

Correction to "Light-Induced Transformation from Covalent to Supramolecular Polymer Networks".

ACS macro letters·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 17, 2025

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Published on: June 20, 2019

Modeling Microstructure Formation in Block Copolymer Membranes Using Dynamical Self-Consistent Field Theory.

Douglas J Grzetic¹, Anthony J Cooper², Kris T Delaney¹

¹Materials Research Laboratory, University of California, Santa Barbara, California93106, United States.

ACS Macro Letters

|December 15, 2022

Summary

This summary is machine-generated.

Block copolymer membranes for ultrafiltration require specific solvent and nonsolvent properties. Opposite block selectivities during nonsolvent-induced phase separation (SNIPS) are crucial for forming desired porous structures.

More Related Videos

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

Measuring the Time-Evolution of Nanoscale Materials with Stopped-Flow and Small-Angle Neutron Scattering

Measuring the Time-Evolution of Nanoscale Materials with Stopped-Flow and Small-Angle Neutron Scattering

Published on: August 6, 2021

Related Experiment Videos

Last Updated: Aug 17, 2025

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers

Published on: June 20, 2019

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

Measuring the Time-Evolution of Nanoscale Materials with Stopped-Flow and Small-Angle Neutron Scattering

Measuring the Time-Evolution of Nanoscale Materials with Stopped-Flow and Small-Angle Neutron Scattering

Published on: August 6, 2021

Area of Science:

Polymer science
Materials science
Chemical engineering

Background:

Block copolymers are promising for ultrafiltration membranes due to self-assembly and nonsolvent-induced phase separation (SNIPS).
Understanding the relationship between processing variables and membrane morphology is critical for optimizing performance.
The interplay between microphase and macrophase separation during SNIPS in block copolymers is not fully understood.

Purpose of the Study:

To investigate the microstructure evolution of block copolymer films during SNIPS.
To determine the influence of solvent and nonsolvent selectivity on membrane morphology.
To elucidate the conditions necessary for forming isoporous integral-asymmetric membranes.

Main Methods:

Dynamical self-consistent field theory simulations were employed.
Simulations focused on the microstructure evolution of block copolymer films during the SNIPS process.
Analysis centered on the impact of solvent and nonsolvent block selectivities.

Main Results:

Block copolymer films formed the desired sponge-like asymmetric porous substructure only when the solvent and nonsolvent exhibited opposite block selectivities.
When solvent and nonsolvent had similar block selectivities, dense, nonporous, microphase-separated films were produced.
The study highlights the critical role of solvent-nonsolvent interactions in controlling membrane architecture.

Conclusions:

The choice of solvent and nonsolvent is a key determinant in fabricating effective block copolymer ultrafiltration membranes.
Opposite block selectivities are essential for achieving the desired porous structure via SNIPS.
These findings provide critical guidance for the rational design and processing of advanced block copolymer membranes.