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Related Concept Videos

Quality Control01:05

Quality Control

233
Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
233
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

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Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
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Methods of Sterilization I: Physical Methods01:29

Methods of Sterilization I: Physical Methods

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As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
20.5K
Methods of Sterilization II: Chemical Methods01:30

Methods of Sterilization II: Chemical Methods

6.8K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
6.8K
Standard Precaution01:26

Standard Precaution

2.1K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.1K
Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

181
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
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Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies
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The need for systematic quality controls in implementing N95 reprocessing and sterilization.

N Goyal1, D Goldrich1, W Hazard2

  • 1Department of Otolaryngology - Head and Neck Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.

The Journal of Hospital Infection
|December 15, 2022
PubMed
Summary
This summary is machine-generated.

Quality control measures successfully enabled N95 mask reprocessing for reuse during the pandemic. Real-world clinical testing is crucial for ensuring mask integrity and safety beyond laboratory conditions.

Keywords:
COVID-19Hospital safetyInfection controlMask reprocessingN95PandemicQuality controlQuality improvementSARS-COV-2Sterilization

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Area of Science:

  • Healthcare Management
  • Infection Control
  • Materials Science

Background:

  • The COVID-19 pandemic increased demand for personal protective equipment (PPE), leading to N95 mask reuse via sterilization systems.
  • Few studies have addressed the clinical challenges and quality control (QC) in N95 mask reprocessing.

Purpose of the Study:

  • To demonstrate successful implementation of QC measures for N95 mask reprocessing.
  • To emphasize the importance of ongoing quality assurance in mask reuse programs.

Main Methods:

  • A prospective quality improvement study evaluated 982 N95 masks (3M 1860 and Kimberly-Clark PFR95) using vaporized hydrogen peroxide gas plasma.
  • Post-processing qualitative fit testing (QFT) was performed on 265 masks.
  • National Institute for Occupational Safety and Health (NIOSH) mannequin testing assessed filtration efficacy and fit after sterilization cycles.

Main Results:

  • 12.2% of 3M masks and 28.5% of PFR95 masks failed post-processing QFT.
  • Failure reasons included mask deformation, soiling, weakened elastic bands, and shrinkage.
  • NIOSH testing showed filter efficiency remained >98% after two cycles, but strap elasticity decreased by 5.6%.

Conclusions:

  • Successful implementation of QC measures for N95 mask disinfection was demonstrated.
  • Real-world clinical testing is vital for evaluating mask reprocessing effectiveness beyond controlled laboratory settings.